Spray drying, Pharmaceuticals and cosmetics

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Spray drying

Description

Particle formation for lab scale

BUCHI’s proven, reliable and versatile solutions for Spray Drying cover a broad range of applications. Discover the time- and cost-saving solutions for R&D particle formation.

Your advantages
∙ Continuous process
∙ Short process time (up to 1 L/h)
∙ Low cost at industrial scale∙
∙ Protection of core material
∙ Mild drying conditions
∙ Scale-up your process to high product volumes
∙ High yields obtained (< 90%)
∙ Controllable particle size and morphology (0.3 – 60 µm)
∙ Shortest process times and fast cleaning
∙ Work with low flow rates and small sample volumes
∙ Process control due to glass assembly
∙ With the Mini Spray Dryer B-290 or with the Nano Spray Dryer B-90 with the Inert Loop B-295 it is possible to spray with organic solvents without risk of explosion, because the system works under inert conditions.

Solution «Spray Drying Small» (300 nm – 5 µm). Laboratory Spray Drying for small samples and particles. You deal with expensive sample materials or want to obtain the smallest particles. (Spray Dryer: Nano Spray Dryer B-90, Organic solvent trap: Inert Loop B-295, Gas circulator: Aspirator, Water trap: Dehumidifier B-296 & Upgrade Set, Air conditioner: Dehumidifier B-296 & Upgrade Set, Drying gas source: Aspirator & inlet filter)
Solution «Spray Drying Medium» (2 – 25 µm) Laboratory Spray Drying at high throughput with maximum possibilities. ∙ Organic, acidic or aqueous samples: Mini Spray Dryer B-290, Organic solvent trap: Inert Loop B-295, Water trap: Dehumidifier B-296, Air conditioner: Dehumidifier B-296, Higher yields: High performance cyclone, Congealing: Spray Chilling ∙ Immiscible samples: Three-fluid nozzle)
Solution «Spray Drying Large» (10 – 60 µm) Laboratory Spray Drying with maximized particle size Spray Dryer: Mini Spray Dryer B-290 Advanced, Larger Particles: Ultrasonic package, Organic solvent trap: Inert Loop B-295, Air conditioner: Dehumidifier B-296)

What is the functional principle of the laboratory spray dryer ?
Step 1 Heating: Heat the inlet air to the desired temperature (max. 220 °C)
Step 2 Droplet formation: Two-fluid nozzle for the B-290 and ultrasonic spray head for the B-90
Step 3 Drying chamber: Conductive heat exchange between drying gas and sample droplets
Step 4 Particle collection: Cyclone technology for the B-290 and electrostatic particle collector for the B-90
Step 5 Outlet filter: Collection of finest particles to protect the user and the environment
Step 6 Drying gas: Delivered by aspirator for the B-290 and by aspirator or compressed air for the B-90
Step 7 Filtering of the drying gas

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