Glass-, glass lined steel reactor: 15, 30, 60, 100, 160, 250 liter
Pressure: -1.0 (FV) to +0.5 bar
Temperature: -60 °C (-90°C) to +200 °C
Material: Borosilicate glass 3.3, glass lined steel, PTFE, PFA, Tantalum
• Hastelloy, other materials, other designs on request
Multipurpose glass pilot reactor and pilot plant
Performance and reliability are key issues in the explosion proof design of Buchi glass reaction systems: The inert materials allow safe processing in a inert atmosphere of a wide range of solvents and acids in a completely sealed glass reaction system under full vacuum. Multiple chemical reaction steps are performed safely in the same setup. The system consists of:
Reactor with solid jacketed glass lined steel bottom stands for solid construction, excellent heat transfer, stable process conditions and temperatures, and a glass section to easily improve and control chemical reactions by visual observation.
Distillation glass overhead built with buchiflex components (unique flexible ball - socket joints) for mulitple, reliable processes under full vacuum.
The CR type chemReactor is a multipurpose pilot reactor system for chemical process development, scale-up, process simulation and kilo-scale cGMP production in batch and semi-batch operation.
We produce complete solutions for chemical processing: Reactor systems including accessories like sampling devices, pH probes, rectification columns with structured packing, process monitoring and control as well as integration of auxiliary equipment such as temperature control units, nutsch filters / dryers, scrubbers or mixing vessels.
Standard package
• Jacketed full glass / glass lined steel reactor
• Multipurpose glass distillation overhead
• Stainless steel frame, supporting flexible glass superstructure
• ATEX Zone 1 (0) / CE / cGMP
• CIP capable
• FDA conform, highly corrosion resistant
• Complete documentation
Standard options
• Reactor lift for easy opening (vessel cleaning)
• Sampling device
• pH monitoring and control
• Gas introduction (Nitrogen purging and active gas)
• Vacuum / exhaust piping
• Additional feeders / receivers
• Solid feeding
• Cryogenic vessel for low temperature chemistry (-90°C)
• in special glass lining or Hastelloy C22
• mixed systems with pressure reactor and vacuum distillation
• IQ / OQ / PQ
Reactor vessel • jacketed glass lined steel vessel with glass section
• 15, 30, 60, 100, 160, 250 liter
• Glass lined steel impeller stirrer
• Glass lined steel baffle
• Flush mounted drain valve
Glass dome / Glass lined cover plate • Glass cover dome (15, 30 liter)
• Glass lined steel cover (60, 100, 160, 250 liter)
• Fast-action closure for addition of solids
• 8 connection nozzles
ATEX stirrer drive • ATEX motor and adjustable transmission
• ATEX dry running mechanical seal
• Glass lined impeller stirrer
Lifting / lowering device (optional)• Easy opening/closing of the reactor vessel
• Easy access for cleaning
All Buchi chemReactors (15 - 250 liters) are available with vertical condensers and in the compact K - design. 
Distillation glass overhead• Unique flexible ball-socket joints
• Feed vessel for liquid addition
• Distillation column / vapor duct with pressure gauge and bursting disc
• Spiral condenser with vacuum / exhaust connection
• Vertical condensers or horizontal setup (compact design)
• Receiver vessel for collection of distillate
• Dean stark phase separator
• Vacuum / pressure equalization and distribution piping
• Self-draining «buchiflex» glass piping
• Vacuum distillation
• Azeotropic distillation (phase separation)
• Evaporation to any desired consistency
• Multi-component chemical reactions
• Gas introduction into liquid phase
• Chemical synthesis
• Extraction of multi phase mixture
• Crystallization
• Refluxing
• Multiple chemical reactions liquid/liquid, liquid/solid
• Low temperature chemistry